Recording sympathetic nerve activity chronically in rats: surgery techniques, assessment of nerve activity, and quantification
نویسندگان
چکیده
منابع مشابه
Recording sympathetic nerve activity chronically in rats: surgery techniques, assessment of nerve activity, and quantification.
The sympathetic nervous system plays a pivotal role in homeostasis through its direct innervation and functional impact on a variety of end organs. In rats, a number of methods are available to assess sympathetic nervous system function. Traditionally, direct recording of sympathetic nerve activity (SNA) has been restricted to acute, anesthetized preparations or conscious animals within a few d...
متن کاملCafeteria diet increases fat mass and chronically elevates lumbar sympathetic nerve activity in rats.
Obesity causes sympathetic activation that promotes atherosclerosis, end-organ damage, and hypertension. Because high-fat induced weight gain in rats elevates plasma leptin at 1 to 3 days after the onset of calorie-dense diets, we hypothesized that diet-induced overfeeding will increase sympathetic activity within 1 week after the onset of the regimen. To test this, we continuously measured sym...
متن کاملSympathetic Nerve Activity in Humans
In nine sedentary subjects (16.5±0.4 years, mean±SEM) we measured blood pressure (Finapres device), heart rate (electrocardiogram), and postganglionic muscle sympathetic nerve activity (micToneurography from the peroneal nerve) at rest and during intravenous infusion of phenylephrine and nitroprusside. These measurements were performed before and after 10 weeks of endurance training (2 h/d, 5 d...
متن کاملUrethane suppresses renal sympathetic nerve activity in Wistar rats.
AIM To investigate the effects of urethane on renal sympathetic nerve activity (RSNA) in Wistar rats. MATERIALSAND METHODS 46 rats were randomly allocated in two groups: group A in which rats were injected with urethane; group B in which barbital sodium was used as a control. The changes of RSNA, blood pressure (BP) and heart rate (HR) of each group were evaluated and analyzed. RESULTS Comp...
متن کاملSympathetic Nerve Activity in Monozygotic Twins
Hypertension constitutes a major risk factor for cardiovascular disease and for the total disease burden in the world today. Traditionally, focus has been on the resting blood pressure level, but blood pressure variability has received increasing attention, and several studies have found that increased 24-hour blood pressure variability is associated with increased target-organ damage. Although...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 2013
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.00173.2013